The purpose of this study is to establish the performances of Cell Bound Complement Activation Products in (1) monitoring SLE disease activity and predicting flares, and (2) differentiating subjects with SLE from those with other similar rheumatic diseases. Another objective is to identify genetic biomarkers associated with SLE and its’ clinical manifestations. Participation includes a total of 13 study visits consisting of a blood draw, urinalysis, and physical exam.
To perform analysis of immune system cellular subsets using peripheral blood samples collected from patients with active SLE during the natural course of disease and treatment and compare SCNP data from these samples with similar data obtained from healthy individuals.
NUgene is a clinical research project currently being conducted at NMH and NMFF. The goal of this project is to collect and store genetic samples (DNA) along with associated healthcare information to form a gene bank. This large bank of samples, currently at 9,600 and growing, is available to researchers who are working to identify genetic contributions to human disease. This allows the researchers to more easily obtain many samples at one time, facilitating genetic research so it can more quickly impact healthcare in the future. All samples and information are de-identified before distribution for research.
Participants in this study have the opportunity to provide Dr. Ramsey-Goldman with access to the information collected from participants through NUgene for research purposes. This will allow her to do additional research in the future on the role that genes play in lupus.
The overall goal of this study is to determine the relationship between two constructs, fatigue and physical activity, as a critical first step in a broader effort to implement a behavior management intervention that combats fatigue by increasing lifestyle physical activity in persons with SLE.
The lupus research group has taken on a new initiative, the Roadmap for Education and Access to Care for Chicago Hispanic Lupus (REACH LUPUS) Disparities Project which is funded by the ACR to work with a targeted Hispanic-Mexican population in Chicago’s Pilsen community to increase lu-pus awareness where individuals diagnosed with conditions such as lupus that have few recourses for care, follow-up and continued treatment using educational materials. The project has been recently funded and is still in early program development. The project design is multifaceted and will include work provided to the community via support group services and to primary providers by engaging in outreach and education.
A 6 week intensive program which combines the following goals:
• 10% increase in physical activity
• Change in calorie distribution to include more fruits and vegetables
The intervention is a unique combination of two individual sessions and three group sessions, providing both a tailored personalized intervention and the benefits of group learning and support. Healthy Living Coaches will be responsible for leading assigned group sessions and will conduct individual sessions for a limited caseload of participants.
Through a partnership with the University of Alabama and lupus centers around the world, we are currently engaged in research to examine genetic and environmental risk factors for organ damage in people with lupus. We are now recruiting Caucasian, African-American, and Hispanic men and women at least 19 years of age for this study. Study participation involves three annual visits that include a blood draw, urinalysis, and physical exam.
The purpose of this study is to develop a registry or database of information on a large number of newly diagnosed SLE patients who are followed by the 30 SLICC members over time. This registry will provide the long term follow-up of a large diverse population of patients using standard methodologies. This will allow researchers to determine the prevalence and nature of early atherosclerotic coronary artery disease in SLE and to identify associated risk factors.
The purpose of this study is to find out the effects of lupus on blood vessels and on long-term bone conditions. Participants are women with lupus (cases) and women without lupus (controls) who complete three study visits over a five-year period. Study visits include a carotid ultrasound, bone density test, x-ray of the heart, physical exam (cases), urinalysis, and blood testing (including glucose and cholesterol screening).
For more information about the Chicago Lupus Database or our research studies, please contact us via email at firstname.lastname@example.org.